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Systematic documentation of adverse effects and physical changes enables early problem recognition and supports clinical decision-making

Specifically, there was a shortage of research regarding the relationship between GLP-1 agonists and acne

Triple agonists that target GLP-1, GIP, and glucagon receptors, such as retatrutide, are also in development and have shown even greater weight loss effects in early-phase trials

The medication works at the level of the nervous system and pancreas, not by changing how your small intestine processes food

Funding This study was supported by the Natural Science Foundation Project of Hunan province (2023JJ40917 and 2025JJ50624) and the Changsha Natural Science Foundation (kq2403192)