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The bioavailability (how much drug reaches your bloodstream) may differ between delivery methods

However, semaglutide slows stomach emptying, which may modestly affect levothyroxine absorption

So, even when compounded semaglutide contains the same active ingredient as Ozempic, semaglutide base, and is prepared by a state-licensed compounding pharmacy, we cannot say that it is as effective as Ozempic or Wegovy simply because it has not been studied and gone through FDA approval process

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