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[4] For weight management, clinically meaningful weight loss is generally defined as 5% or more of initial body weight

These medications are only reimbursed when used for their FDAapproved uses, such as type 2 diabetes, not obesity

GLP-1s may drive 0.2%0.5% annual mortality improvement, realized over a 20-year period
Targeting 0.7-1.0 grams of protein per pound of goal body weight helps preserve lean mass

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