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A good metric to consider is this: If an obese patient (BMI 30 to 34.9) is on a GLP-1 for six months and has not reached 10% TBWL, they should be referred back to their primary care provider to reassess their weight-loss plan

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doi:10.1002/14651858.CD012990.pub2 200

The mean eGFR at baseline was 87 mL/min/1.73 m2 and 7% of the patients had an eGFR less than 60 mL/min/1.73 m2

Effects on glucose metabolism Increased insulin secretion in a glucose-dependent manner Decreased glucagon secretion Increased insulin sensitivity Possible decrease in blood glucose due to the above-mentioned effects