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Classic agonists like liraglutide, semaglutide, and dulaglutide mimic the natural signal but keep it on far longer

the former was only accessible for obesity management, and the latter had not been introduced in Korea

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Furthermore, non-users of GLP-1RAs exhibited more than a twofold higher risk of all-cause mortality compared with GLP-1RA users ( 5.1 Systemic and hepatic efficacy: Correcting metabolic derangements and steatosis As depicted in Figure 1, GLP-1 RAs are highly effective at correcting the core metabolic derangements seen in MASLD/T2DM