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Overweight patients with NAFLD exhibited clinically significant fibrosis (stages F24) at a rate of 20.3%, while obese patients had a slightly higher prevalence at 21.6%
Orforglipron's newer status means less clinical familiarity when patients present with unexpected responses or need guidance combining treatments, creating uncertainty that structured routines don't always resolve

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Circulating MOTS-c levels are decreased in obese male children and adolescents and associated with insulin resistance
