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GLP-1 levels naturally rise and fall in response to eating
We know that this is a problem because studies have shown that patients who use only T4 medications like levothyroxine never obtain normal healthy free T3 levels after thyroid surgery
Peripheral native GLP-1 administration activates c-fos expression in the hindbrain and hypothalamus in rodents (6668), indicating that peripheral GLP-1 actions are activating central circuits
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