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For some patients, the condition becomes disabling: Persistent vomiting can lead to dehydration, electrolyte imbalance, and emergency care Inadequate nutrition can cause weight loss and malnutrition unrelated to intentional weight loss Symptoms may persist even after discontinuing the drug, requiring ongoing medical management Plaintiffs allege there is no cure for gastroparesis and that treatment can be long-term, involving dietary restrictions, medications, IV fluids, feeding tubes, or procedures aimed at improving gastric emptying

Waistlines shrank by over 10 centimeters on average, and metabolic health markers like HbA1c and LDL cholesterol continued to trend in a favorable direction

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People with the genetic condition Prader-Willi syndrome (PWS) also struggle with high body weight, but GLP-1 inhibitors appear to have no effect in reducing their hunger (1)