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glp 1 gip dual agonist mechanism of action Mechanisms and effects of GLP‐1 receptor agonists and The Effects of Dual GLP-1/GIP
Description
Characterizing a new tool to manipulate area postrema GLP1R+ neurons across species

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These specialized regions detect circulating GLP-1 and GLP-1RAs and relay signals to the hypothalamus, further influencing appetite and body weight regulation

Hsia DS, Grove O, Cefalu WT

And what happens to weight trajectories after treatment stops is unknown in this age group, though the adult discontinuation data from SURMOUNT-4 suggest substantial rebound
