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2021;9:e002146

To conclude, we have shown that the GLP-1RA semaglutide reduces BW through direct effects in the hypothalamus and the hindbrain as well as secondary effects in several areas previously described to be involved in energy metabolism

decreased the gluconeogenesis, and decreased plasma-free fatty acid's level, plasma triglyceride, total cholesterol levels and corticosterone level, while increasing plasma leptin (the satiety hormone)

An assigned clinical research associate (CRA) conducts fortnightly site visits during clinical sessions to verify and maintain recorded data quality

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