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Cervical vagotomy resulted in an immediate increase in heart rate ( Figure 3A ) and blood pressure (see Supplementary material online, Figure S3A )

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Discussion In this database study, treatment with semaglutide (against sitagliptin, a placebo proxy) led to a reduced risk of MACE, and tirzepatide (against dulaglutide) demonstrated a similar risk reduction in patients at elevated cardiovascular risk with obesity and type 2 diabetes

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doi: 10.1016/j.coph.2016.08.005 [DOI] [PubMed] [Google Scholar] 110

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