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This can lead to issues like constipation, vomiting, and problems with nutrient and water absorption

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This stage, called Hurley Stage II, is characterized by recurrent nodules and abscesses and the first signs of irreversible tissue alterations defined by the formation of early sinus tracts (dermal tunnels) and early fibrosis scarring [81,82,83] (Fig

Blood glucose, insulin, and leptin levels dropped significantly, and ketone bodies increased fivefold