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In clinical practice, for patients with MetALD and ongoing alcohol use, therapies aimed at controlling alcohol use remain most critical, given the faster, more progressive disease course related to alcohol as compared to metabolic liver injury

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Plateaus during semaglutide or tirzepatide treatment are common and expected

For one, it may support weight management by regulating appetite, so people can manage their calorie intake more effectively

Phase 2a trial found reduced nicotine craving and weight loss with semaglutide, but no significant between-group difference in cigarettes smoked per day.