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You may notice the benefits, such as appetite control or low blood sugar levels, fading gradually

Our current practice is to consider a ~20% bolus insulin decrease and a ~10% basal insulin decrease before GLP-1RA initiation, although prior A1c, risk of hypoglycemia, potential risk of ketosis due to reduced insulin doses, as well as other patient-specific factors should guide the final insulin dose changes

Gastroenterol Hepatol (N Y)

Chris Serres: Honestly, I, Im not aware of a downside