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A 12-week medication course addresses none of these underlying drivers in a permanent way

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These variables meaningfully influence both efficacy and safety, including cardiovascular risk, thrombotic events, and metabolic response

The sympathetic nervous system affects intestinal immune activity, while the HPA axis, the main humoral component of the gut-brain axis, responds to environmental stress or intestinal inflammation by releasing glucocorticoids and then restoring homeostasis or causing GI dysfunction by modulating enteric immune cells, gut function, and microbial composition (415)

The best course of action is to seek expert advice from medical clinicians who specialize in hair health