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Given the observed increased risk of colorectal cancer among patients receiving GLP-1 receptor agonists, clinicians should approach long-term prescribing of these agents with careful consideration, particularly in individuals with additional risk factors for colorectal cancer, such as a family history, obesity, inflammatory bowel disease, or long-standing type 2 diabetes

Thus, the ChIP-seq analysis uncovered many genes bound by LAG-1 in the germline, whether GLP-1 signaling regulates these genes is not clear

Persistent nodules should be evaluated by your healthcare provider
Chang, Y
