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PLoS ONE 6 , e22781 (2011)

This finding underscores that obesity is a chronic disease requiring ongoing management rather than a condition that can be permanently "cured" with temporary intervention

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The documented protocol starts at 2.5 mg once weekly as a tolerability dose, then titrates up roughly every four weeks 5, 7.5, 10, 12.5, up to a 15 mg maximum maintenance dose
