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Assessing Cardiovascular Safety and Outcomes With the Combination of Cagrilintide and Semaglutide (CagriSema): REDEFINE 3 Randomised Clinical Trial Baseline Characteristics and Methods
Its premise is an upstream intervention targeting substantial weight reduction to improve key risk factors with the aim to avoid potential downstream complications from multiple co-morbidities, e.g., hypertension, dyslipidaemia, heart failure, kidney disease, NAFLD/NASH or diabetes
New use of semaglutide was associated with a lower risk for medical care related to tobacco use disorder in smokers with type 2 diabetes.
Bias probes showed no differential utilization
