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Nature 546 , 248253 (2017)

Across STEP 1 through STEP 3, 82.2% of patients taking semaglutide experienced some form of gastrointestinal adverse event, compared to 53.9% in the placebo group

Pemvidutide, a GLP-1/glucagon dual receptor agonist, significantly reduces liver fat, fibro-inflammation, and body weight in patients with non-alcoholic fatty liver disease: a 24-week multicenter, randomized, double-blind, placebo-controlled trial

While most GLP-1 medications don't directly reduce contraceptive efficacy, severe vomiting or diarrhoea could affect absorption of oral contraceptives
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