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Rapid or extreme weight loss can accelerate lean mass and bone density decline , potentially increasing frailty and fracture risk

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If you notice new symptoms or changes in your body, discussing these with your provider can lead to adjustments in your treatment plan

Notably, a recent study introduced a predictive model with strong performance (concordance index [C-index] = 0.827, 95% confidence interval [CI] = 0.7720.882) for early detection of ED in subjects with type 2 diabetes (T2D), incorporating variables such as diabetes duration, carotid intima-media thickness (CIMT), and low-density lipoprotein cholesterol (LDL-C) levels [15]

Eur Heart J 2021;42:2565-73