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These medications carry a boxed warning for medullary thyroid carcinoma and are contraindicated in patients with personal or family history of MTC or Multiple Endocrine Neoplasia syndrome type 2
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That changed in 2025 and 2026 with the FDA approval of two oral options: the Wegovy pill (oral semaglutide, approved December 2025) and Foundayo (orforglipron, approved April 2026)
So, it doesnt upset me or frustrate me
