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The phenomenon of Ozempic babies, where individuals can conceive more easily on GLP-1 therapy, underscores how closely metabolic and reproductive health interact

GLP-1R agonists, by regulating insulin release and lowering blood glucose levels, may help improve insulin resistance and glucose metabolism disorders, indirectly protecting the nervous system from damage

Metabolic benefits: Gains in lipid profile, blood pressure, and cardiovascular risk markers [1] [5]

It is the primary anabolic hormone in the body, facilitating glucose uptake into muscle, fat, and liver cells while inhibiting glucose production by the liver

The question, as with combining GLP-1 and GIP receptor activity, is whether adding glucagon receptor activity to GLP-1 receptor activity exceeds the glycaemic lowering and weight loss achieved with a GLP-1 RA alone (Ambury et al, 2018