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Given the theoretical risk, Semaglutide should be avoided in those with a personal or family history of medullary thyroid carcinoma

Pre-existing discomfort can be amplified, making pain more likely

[205] Current research has not definitively established the safety profile of ondansetron in pregnant women, and studies have produced conflicting results regarding potential risks to the developing fetus

doi: 10.1210/jc.2017-00082 162 AdnanZ

After excluding other common causes through clinical assessment and diagnostic workup, this case underscores the importance of recognizing this rare but potentially serious adverse effect of semaglutide