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Lower estrogen encourages fat to accumulate around the abdominal organs

Effects of liraglutide plus phentermine in adults with obesity following 1 year of treatment by liraglutide alone: a randomized placebo-controlled pilot trial

Researchers studied 338 adults with obesity or overweight who did not have diabetes
GLP-1 medications improve insulin sensitivity and reduce hyperinsulinemia, shifting the hormonal environment away from growth-factorrich conditions that may favor lesion survival

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