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Intermittent fasting protocols and MOTS-C have a real overlap

Recently, very long-chain fatty acids glucosylceramides (C22 GlcCer) have been shown to be elevated in glp-1(-) mutants and are crucial for maintaining lysosomal function and promoting longevity 64 , further bolstering a role of sphingolipid metabolism in lifespan regulation

The subgroup and treatment effects on time to first event of MACE by baseline kidney function and albuminuria status were analysed with a stratified Cox proportional hazards model

JAMA Neurol 79(9):846855

This trial tests a new treatment called retatrutide to determine its safety and effectiveness for individuals with obesity and knee osteoarthritis, a joint condition causing pain and stiffness