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Description

The Mayo Clinic cohort: women on semaglutide plus HRT lost more weight at every timepoint (and it wasnt explained by confounders)

Du L, Qin J, Wang D, et al

GLP1-R is a class B G protein-coupled receptor, 25 and its expression has been reported in the cerebral cortex, especially the occipital and frontal lobes, hypothalamus, and thalamus, whereas lower levels are found in the caudate putamen, globus pallidus, and hippocampus

(UK) al

GLP-1 infusion on food intake was lost after truncal vagotomy [695], indicating that vagal afferents are involved in mediating the effects of circulating native GLP-1 on appetite