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New York facial plastic surgeon and obesity medicine specialist Melynda Barnes, MD, chief medical officer at Ro, agrees
The unique advantage of retatrutide, its ability to increase energy expenditure and fat oxidation beyond what GLP-1/GIP alone achieve, may depend on reaching peak concentrations that only weekly dosing reliably provides

SELECT trial shows GLP-1 goes beyond weight

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However, the body views energy conservation as a survival priority
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