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doi: 10.1016/j.molmet.2021.101181 32 stergaardSPaulssonJFKofoedJZoselFOlsenJJeppesenCBet al

127 GCGR knockout is detrimental in mice as 50% did not survive until birth in this study

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This timeframe generally corresponds with the body's adaptation period to the medication and its metabolic effects
