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When combined with insulin or sulfonylureas, dose adjustments of these medications are frequently necessary to reduce the risk of hypoglycemia, as the glucose-lowering effects may be additive

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Initial evaluation of hot flashes should include thyroid function testing and, when relevant, pregnancy testing

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As a result of these findings, the collaborators suggested 'proglucagon 78-107 may be the incretin of the lower gut' (Holst, rskov, Vagn Nielsen, Schwartz)