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A study into the effect of these drugs on cancer pathways associated with obesity could yield significant knowledge regarding their potential advantages beyond weight control [11, 36, 66, 98]

By activating these receptors, it modulates metabolic pathways to reduce appetite, enhance insulin sensitivity, promote energy expenditure, and regulate glucose homeostasis, overall contributing to weight loss and improved metabolic function

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Although most studies suggest that GLP-1 receptor agonists promote weight loss primarily due to their inhibitory effect on food intake, other central impacts that have been described for native GLP-1 and some GLP-1 receptor agonists in rodents and humans inspire future clinical trials to explore additional mechanisms in the CNS

Y., Cheung, T