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However, alcohol can worsen gastrointestinal side effects common with this drug class and can affect blood sugar control, so once the medicine is licensed, patients should follow the prescribers specific guidance

However, add fiber slowly because too much too fast can worsen bloating and discomfort

There were no statistically significant interactions by treatment and background medication subgroup for change in HbA1c or body weight except for change in HbA1c (background insulin vs insulin plus metformin) in PIONEER 8 (p = 0.0408)

This makes them an ideal entry point for anyone looking to achieve noticeable improvements with minimal interruption to their daily routine