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GLP-1 administration induces visceral illness in both rodents (Seeley et al., 2000) and humans (Madsbad et al., 2008)

Below, we summarize key studies evaluating GLP-1R agonism in rodent models of opioid reinforcement, seeking, withdrawal, and relapse

Small, frequent meals work better than large meals when your gastric emptying is pharmacologically slowed

Exenatide improved liver fat content and reduced markers of liver injury in animal models fed a high-fructose diet, highlighting the role of -catenin in mediating these effects (Zhou et al., 2020)

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