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Independently of these peripheral actions, GLP-1RAs show direct cerebral effects in animal stroke models, such as reduction of infarct volume, apoptosis, oxidative stress, neuroinflammation, excitotoxicity, bloodbrain barrier permeability, and increased neurogenesis, neuroplasticity, angiogenesis, and brain perfusion

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This phenomenon refers to sagging skin or a deflated appearance in the buttocks, sometimes seen in individuals who use Ozempic for weight loss

Selina Wang reports on Medicares $50 GLP-1 weight-loss drug program, while Heidi Skolnik breaks down long-term benefits, risks and how patients should approach use of the medications.