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doi: 10.1007/s40263-015-0301-8 24 MuscogiuriGDeFronzoRAGastaldelliAHolstJJ

When volume is limited, every set needs to deliver maximum value

Since the beginning of the year, tirzepatide (marketed as Zepbound and Mounjaro) developer Eli Lilly, which launched its oral GLP-1 orforglipron (marketed as Foundayo) in April 2026, has seen its stock skid roughly 10-13% year-to-date, even as it raised full-year revenue guidance to $82-$85 billion on the strength of Mounjaro and Zepbound volume growth

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Patients treated with GLP-1 medicines had a lower risk of alcohol-related events compared to individuals administered DPP4 inhibitors 54 with greater evidence for benefit during the first 3 months of treatment