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Most patients tolerate the medications well after the initial adjustment period

Ongoing psychological support can identify early warning signs and respond before a full relapse takes hold

Over-the-counter alternatives like orlistat delivered only 23% incremental weight loss in 2024 meta-analyses, reinforcing prescriber reliance on higher-efficacy options
doi: 10.1126/scitranslmed.adj0052 101 ArvidssonACollinTKirikDKokaiaZLindvallO
