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The broader category of weight loss peptides leverages these same GLP-1 pathways

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Figure 1: Mean Change from Baseline for A1C (%) over 24 Weeks with Sitagliptin and Metformin, Alone and in Combination as Initial Therapy in Patients with Type 2 Diabetes Mellitus* *All Patients Treated Population: least squares means adjusted for prior antihyperglycemic therapy and baseline value

Many payers impose step-therapy (fail cheaper diabetes or weight-loss medications) and time-limited approvals (e.g

And if I stop, will the binges come back even worse? Its a valid fear