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PlexusDx Precision Peptide Genetic Test analyzes variants in GLP1R, GIPR, FTO, and MC4R genes that influence semaglutide responsiveness and side effect risk

The precise shape of the plateau and how it compares dose-for-dose with tirzepatide's trajectory will be clearer once the full peer-reviewed dataset and remaining TRIUMPH readouts are published

At current U.S

Although it shared similarities with weight management trials in design and dosing, BP reductions were more modest (3.3 mm Hg SBP, 0.6 mm Hg DBP), likely reflecting the high baseline cardiovascular risk and widespread use of antihypertensive drugs in the study population
