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Description
Other notable side effects include injection site reactions (redness, itching, or swelling at the injection site), fatigue, and hypoglycemia, particularly when tirzepatide is used in combination with insulin or sulfonylureas

Here is the practical reality

Insulin sensitivity starts improving

Monitor blood sugar more frequently during the first four to six weeks after switching

However, these effects are usually temporary, peaking within days of dose increases and improving significantly over the following 2 to 3 weeks as your body adapts
