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August 12 Product: Ascendis Pharmas Yorvipath Indication: Hypoparathyroidism After a long regulatory road, Ascendis Pharma received FDA approval Monday for Yorvipath (TransCon PTH) for the treatment of hypoparathyroidism, a rare endocrine disease characterized by abnormally low levels of the parathyroid hormone

43 Therefore, discontinuation of treatmentprimarily due to cost and access limitationsremains the major barrier to the widespread and sustainable use of these agents

A meta-analysis of nine observational studies, involving 338 KTRs with a median follow-up time of 12 months, found that treatment with GLP-1 RAs was associated with a decrease in proteinuria but did not significantly alter eGFR levels [22]

Overall, nearly 93% of trial participants lost 5% or more of their body weight, nearly seven times the weight loss achieved by a control group given a placebo, researchers said

P = 0.009) or metformin (OR = 2.58
