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While it has been praised for its effectiveness, some people report unexpected side effects, including mood changes such as irritability

Alcohol and Diabetes Recommendation

Though side effects may feel challenging initially, most patients find them manageable with proper support and careful adherence to management strategies

Of the randomized patients, 63% of those in the sitagliptin group and 59% of those in the glipizide group achieved an HbA 1c of below 7%, whereas 29% of those in each group achieved an HbA 1c of below 6.5%

The higher doses used for weight loss relative to the doses used for diabetes management are hypothesized to prolong gastric emptying, however this association has not yet been confirmed