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10.1007/s40265-020-01435-4 Drugs

In fact, this study shows that the levels of these molecules are significantly lower in joint fluid than in the blood/plasma and may be incidental to the function of the joints. Jeffrey Zarin, MD Also, there did not seem to be a difference between patients that had arthritis and those that did not, so conclusions about the effect of GLP-1 on arthritis should also be interpreted cautiously, Zarin added

These agents mimic the incretin hormones, which enhance insulin secretion and suppress glucagon release, leading to potent effects on weight reduction and glycemic control

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Clinical trials indicate that tirzepatide surpasses the weight loss achieved with some other GLP-1 receptor agonists