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279,280 One study found that GLP-1R is expressed in human hepatocytes obtained from liver biopsies, and treatment with GLP-1 analogues enhanced insulin sensitivity and fatty-acid catabolism, suggesting that these analogues could improve hepatic insulin resistance in patients with nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

Wegovy (semaglutide 2.4 mg) is a prescription medicine authorised by the Medicines and Healthcare products Regulatory Agency (MHRA) for weight management in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related health condition

So even without significant weight gain, not weight, not because you're eating more or moving less, there's an increase in visceral fat being deposited

Skipping dose increases or adjusting schedules without medical guidance can reduce effectiveness or increase side effects

Balkan Medical Journal, 30 (2), 248-249