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Injection-site reactions and worsening of pre-existing diabetic retinopathy are also relevant clinical concerns

Tirzepatide was associated with greater relative lean body mass (LBM) loss than semaglutide at each measured time point, with excess LBM losses of 1.1%, 1.5%, 1.3% and 2% at 3, 6, 9 and 12 months, respectively

Its important to talk with a healthcare provider about how long to use these medicines and make long-term healthy lifestyle changes to help keep weight off for good.What are the side effects?Common side effects include nausea, vomiting, diarrhea, abdominal pain, or constipation

In crude analyses, GLP-1 receptor agonist use was associated with an increased incidence of suicidality compared with DPP-4 inhibitors (crude incidence rates 3.9 v 1.8 per 1000 person years, respectively

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