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In T2DM patients, insulin cannot regulate hepatic glycogen synthesis or glucose production, and increased hepatic gluconeogenesis is the primary cause of fasting hyperglycemia in T2DM [25]

GLP-1 receptor agonists are potent insulin sensitisers, explains Sonia Gibson, MD, a board-certified physician in endocrinology, diabetes, and metabolism, and the endocrinology physician lead at Allara Health

Regul Pept, 125:173-177
