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Recently, the World Health Organization published its first guide on the use of therapies based on glucagon-like peptide 1 (GLP-1) analogues to treat obesity as a chronic, recurrent disease, recommending the use of GLP-1 therapies in adults, excluding pregnant women, for the long-term management of obesity

Yes, metformin and semaglutide are frequently combined and generally compatible

Merck, which has claimed bragging rights as the maker of the worlds best-selling drug, Keytruda, since 2023, has officially been surpassed by Eli Lilly

doi:10.1016/S0140-6736(19)31149-3

But before you consider it, you need to understand what you are actually putting into your body and what the research says about the risks