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Perinatal mortality and congenital anomalies in babies of women with type 1 or type 2 diabetes in England, Wales, and Northern Ireland: population based study

(12) The growing number of orthopedic patients with obesity thus underscores an urgent need for interventions that target both weight reduction and metabolic optimization, offering the potential to improve overall surgical safety and long-term musculoskeletal health

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Towards tailored obesity treatment choices based on obesity-related complications Ectopic fat deposition in different organs results over time in progressive metabolic dysfunction and the development of organ-specific metabolic complications including T2D, MASLD/MASH and HFpEF [108]