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Characterization of the glucagonlike peptide-1 receptor in male mouse brain using a novel antibody and in situ hybridization

The drugs ability to induce weight loss and improve metabolic parameters presents a novel tool in the fight against obesity, a condition that affects a significant portion of the global population and contributes to the risk of numerous health complications, including cardiovascular disease

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In the STEP trials evaluating semaglutide for weight management in individuals without diabetes, participants demonstrated reductions in HOMA-IR alongside substantial weight loss