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While off-label use of Ozempic for weight loss is suspected, 4 this review excludes weight-related outcomes due to a previous CADTH Reimbursement Review that did not recommend reimbursement of a similar SEM medication (Wegovy) for chronic weight management, including in those with T2DM

Do not administer the medicine without this confirmation

The liver fat reduction data from retatrutide is unlike anything seen with other medications

Heart failure with preserved ejection fraction (HFpEF) accounts for approximately half of all heart failure cases, with patients bearing a high symptomatic burden and physical limitations that impact their daily lives

LH and FSH will be suppressed during use