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Bioavailability: Even with SNAC technology, oral semaglutide has only 0.4-1% bioavailability compared to injectable semaglutide

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[Laughs.] Brookshire: Yeah

6 Alternatively, some patients may be prescribed sulfonylureas or thiazolidiniones to improve insulin secretion, but both of these treatment options are associated with an elevated risk of heart failure making them unsuitable for use in patients with cardiovascular disease
