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Description

As the presented experiments do not report absolute changes in alcohol drinking after GLP-1R agonist treatment, the effectiveness of the different agonists cannot be compared

If patients experience severe gastrointestinal symptoms or dehydration, stopping GLP-1 therapy temporarily is advisable

First we increase GLP-1 production

Individual response to GLP-1 therapy depends on dose tolerance, adherence, lifestyle factors, and underlying metabolic health

However, people may present with upper and lower GI symptoms, which can result in delayed diagnosis and treatment, and also represent a more severe phenotype